The Mediterranean region is currently the second most important cruise destination in the world with an increasing trend in recent years. The expansion of the cruise industry in the Mediterranean is due to several factors. Firstly, the development of cruises is supported by the diversity of the Mediterranean region in interesting destinations and the density of the port network which allows the development of innovative cruise routes in a relatively small space and time. Secondly, in the Mediterranean region there have been serious improvements in port infrastructure and security. Thirdly, the global cruise industry is looking for a longer duration in this activity, an opportunity offered in the Mediterranean region due to climatic conditions.